Fondazione Centro Nazionale Di Adroterapia Oncologica (CNAO)
Fondazione Centro Nazionale Di Adroterapia Oncologica (CNAO)
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The National Centre for Oncological Hadrontherapy (CNAO, sited in Pavia, Italy) is a hospital-based facility equipped with a custom synchrotron delivering high-energy scanning ion beams for the treatment of oncological diseases. CNAO is the only centre in Italy providing hadrontherapy with both protons and carbon ions, and one of the 6 dual particle facilities in the world. After an experimental clinical phase (2011-2014), in 2014 CNAO synchrotron achieved CE-mark approval and started fully clinical activity within the frame of the Italian National Health System. To date, CNAO has treated 2800 patients affected by deep-seated tumours or ocular melanoma.
For STOPSTORM CNAO will collaborate with IRCCSOSM. CNAO has previously collaborated with IRCCSOSM on a project that included the cardiac follow-up of patients who received thoracic hadron therapy for cancer purposes, as well the usage of proton therapy to treat refractory ventricular arrhythmias. In the frame of ablative treatment of arrhythmias by RT, ion beams might offer the possibility to greatly reduce dose to surrounding healthy tissues, including critical cardiac substructures. This collaboration led, in December 2019, to the first-time worldwide STAR treatment using proton therapy.
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Dr. Viviana Vitolo
Dr. Viviana Vitolo is a senior radiation oncologist at CNAO, with 10 years of experience in particle therapy. In STOPSTORM she will be responsible of the definition of radiotherapy treatment plan, discussion, and final approval.
Dr. Amelia Barcellini
Dr. Amelia Barcellini is a radiation oncologist at CNAO. In STOPSTORM she will be involved in the definition of radiotherapy treatment plan, discussion, and final approval.
Dr. Alfredo Mirandola
Dr. Alfredo Mirandola is a senior medical physicist at CNAO. In STOPSTORM he will be involved in the dose calculation, optimization, discussion, and quality assurance of radiotherapy treatment plans.
Prof. Guido Baroni
Prof. Guido Baroni is Full Professor in Biomedical Engineering at the Department of Electronics Information and Bioengineering of the Politecnico di Milano, and responsible of the Operative Unit of Clinical Bioengineering at CNAO operating in the development and application of image-guidance and adaptive strategies in proton and carbon-ion radiation oncology.
Dr. Roberto Dore
Dr. Roberto Dore is a senior radiologist with expertise in cardiological imaging (incl. MRI and cardio synchronised CT), as well as patient affected by atrial fibrillation. Until 2017 he was the head of the TC and Cardiovascular Unit of the Radiology Department of University Hospital in Pavia. He is Contract Professor of Radiology at the University of Pavia. In this project he will be fully involved in the definition of target volume for RT by means of Cardiac TC and Cardiac MRI.
Publications uitklapper, klik om te openen
- Vai A, Mirandola A, Magro G, et al. Characterization of a MLIC Detector for QA in Scanned Proton and Carbon Ion Beams. Int J Part Ther 2019; 6: 50-9.
- Molinelli S, Russo S, Magro G, et al. Impact of TPS calculation algorithms on dose delivered to the patient in proton therapy treatments. Phys Med Biol 2019; 64: 075016.
- Ciocca M, Mirandola A, Molinelli S, et al. Commissioning of the 4-D treatment delivery system for organ motion management in synchrotron-based scanning ion beams. Phys Med 2016; 32: 1667-71.
- Meschini G, Vai A, Paganelli C, et al. Virtual 4DCT from 4DMRI for the management of respiratory motion in carbon ion therapy of abdominal tumors. Med Phys 2019; 47: 909-16.
- Mastella E, Molinelli S, Pella A, et al. 4D strategies for lung tumors treated with hypofractionated scanning proton beam therapy: Dosimetric impact and robustness to interplay effects. Radiother Oncol 2020; 146: 213-20.
