The University Medical Centre Mannheim (UHEI)
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The University Medical Centre Mannheim (UHEI) is a large tertiary medical centre and university hospital. Over 250.000 patients are cared for annually in around 30 clinics and institutes. The medical departments involved in STOPSTORM are ‘Cardiology, Internal Intensive Care Medicine, Angiology and Pneumology’ and ‘Radiation Oncology’.
The Cardiology Department covers all diagnostic and treatment aspects of supraventricular and ventricular brady- and tachyarrhythmias. Over the past years we have treated 22 (2017), 24 (2018) and 31 (2019) patients, both ischemic and non-ischemic.
The Radiation Oncology Department has many years of experience in image-guided stereotactic radiotherapy and motion management. This includes the use of breath-hold gating with ABC™ (Elekta) and/or surface tracking (Catalyst™, C-RAD) for SBRT treatments of primary and secondary lung and liver tumours, oligometastases (bone, lung, liver, adrenal, lymph nodes). The department is also an active member of the Working Group Stereotactic Radiotherapy of the German Society of Radiation Oncology.
For the RAVENTA study (German multi-centre STAR trial), UHEI has coordinated and performed the first three benchmark cases regarding interdisciplinary target volume definition in a multi-institutional setting (5 university hospitals).
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Dr. Judit Boda-Heggemann
Dr. Judit Boda-Heggemann is a senior consultant for radiation oncology at UHEI. Dr. Boda-Heggemann will be involved in planning and delivery of STAR in eligible patients.
Dr. Boris Rudic
Dr. Boris Rudic is cardiologist and senior consultant for invasive electrophysiology and device therapy at University Medical Centre Mannheim (UHEI). Dr. Rudic will be involved in screening, recruitment and therapy of patients eligible for STAR.
Dr. Daniel Buergy
Dr. Daniel Buergy is a senior radiation oncologist at UHEI oncology and head of the clinical trials unit at the Department of Radiation Oncology at the University Medical Centre Mannheim. Dr. Buergy will be involved in planning and delivery of STAR in eligible patients and will coordinate study activities within STOPSTORM.
Dr. Jens Fleckenstein
Dr. Jens Fleckenstein is a senior physicist for radiation oncology at UHEI and will be involved in planning and QA of STAR treatments.
Publications uitklapper, klik om te openen
- Rudic B, Chaykovskaya M, Tsyganov A, et al. Simultaneous Non-Invasive Epicardial and Endocardial Mapping in Patients With Brugada Syndrome: New Insights Into Arrhythmia Mechanisms. J Am Heart Assoc 5: e004095.
- Gauter-Fleckenstein B, Nguyen J, Jahnke L, et al. Interaction between CIEDs and modern radiotherapy techniques: Flattening filter free-VMAT, dose-rate effects, scatter radiation, and neutron-generating energies. Radiother Oncol 2020; S0167-8140: 33507-8.
- Boda-Heggemann J, Sihono DSK, Streb L, et al. Ultrasound-based repositioning and real-time monitoring for abdominal SBRT in DIBH. Phys Med 2019; 65: 46-52
- Boda-Heggemann J, Jahnke A, Chan MKH et al. In-vivo treatment accuracy analysis of active motion-compensated liver SBRT through registration of plan dose to post-therapeutic MRI-morphologic alterations. Radiother Oncol 2019; 134:158-165.
- Boda-Heggemann J, Knopf AC, Simeonova-Chergou A et al. Deep Inspiration Breath Hold-Based Radiation Therapy: A Clinical review. Int J Radiat Oncol Biol Phys 2016; 94: 478-92.
- Boda-Heggemann J, Blanck O, Mehrhof F, Ernst F, Buergy D, Fleckenstein J, Tülümen E, Krug D, Siebert FA, Zaman A, Kluge AK, Parwani AS, Andratschke N, Mayinger MC, Ehrbar S, Saguner AM, Celik E, Baus WW, Stauber A, Vogel L, Schweikard A, Budach V, Dunst J, Boldt LH, Bonnemeier H, Rudic B.Int J. Interdisciplinary Clinical Target Volume Generation for Cardiac Radioablation: Multicenter Benchmarking for the RAdiosurgery for VENtricular TAchycardia (RAVENTA) Trial. Radiat Oncol Biol Phys. 2021 Jul 1;110(3):745-756. doi: 10.1016/j.ijrobp.2021.01.028.